Cell Differentiation Symposium PCM-ICB-UFRJ

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3rd Cell Differentiation Symposium - PCM - ICB

May 27, 2014 - Auditorium of the Bloco N of the Centro de Ciências da Saúde

Graduate Program in Morphological Sciences

Biomedical Sciences Institute

Health Sciences Center

Rio de Janeiro Federal University

we are organizing the 3rd Cell Differentiation Symposium of the Graduate Program in Morphological Sciences of the Biomedical Sciences Institute of the Health Sciences Center of Rio de Janeiro Federal University. We will have the participation of Professor Roger Chammas of the Universidade de São Paulo. and Professor Alberto Nobrega, of the Instituto de Microbiologia Prof Paulo de Góes da UFRJ. We will also have the participation of the professors João Menezes, Leonardo Andrade, Manoel Luis Costa e Renato Rozental, all from the Instituto de Ciências Biomédicas da UFRJ.

The provisory Program is:

9:00-9:15

Cláudia Mermelstein

Abertura

9:15-10:00

Radovan Borojevic

Cell Differentiation

10:00-10:20

Manoel Luis Costa

Myogenesis

10:20-10:40

João Menezes

Neurogenesis

10:40-11:00

intervalo

11:00-11:20

Marcia Cury

Differentiation in the Imune System

11:20-11:40

Leonardo Andrade

Differentiation in Epithelial Cells Sensorias

11:40-12:00

Maria Isabel Rossi

Mesechimal Stem Cell Differentiation

12:00-12-30

Roger Chammas

Comparative analysis and discussion

In the afternoon, there will be several short presentations about how each research model relates to the questions discussed in the morning.

13:30-14:00	Cláudia Mermelstein	The role of membrane microdomains in muscle differentiation muscular
14:00-14:30	João Menezes	Neurogenesis at the neuro-immune interface
14:30-15:00	Renato Rozental	Cell-cell comunication in health and in neurological diseases
15:00-15:15		coffe-break
15:15-14:45	Leonardo Andrade	Static or dynamic: the role of sterocilia in sensory celss sensoriais
15:45-16:15	Alberto Nobrega	Differentiation control in lymphocytes
16:15-16:45	Roger Chammas	Cellular de-differentiation in cancer
16:45-17:00	Radovan Borojevic	Closing remarks

We will host a preparatory Cell Differentiation Course, May 19 till 23 with a practical part in several laboratories of the Health Sciences Center.

The Course Program is:

data

2af - 12/3

3af – 13/3

4af - 14/3

5af - 15/3

6af - 16/3

professor

Claudia Mermelstein

Morgana Lima

Leonardo Andrade

João Menezes

Márcia Cury

model

muscle

limphocytes and macrophages

keratinocytes and inner ear tissue explants

neural tissue

bone marrow

The Course is intended for graduate students and researchers. Twenty students will be selected, based on a short description of the reasons for taking the Course, send to manoelluiscosta@ufrj.br.

We are planning on publishing a small report of the Meeting.

This will be the Third Symposium we host: in 2005 we organized the First Simpósio em Diferenciação Celular do PCM with Alberto Nóbrega (UFRJ), Cláudia Mermelstein (UFRJ), Manoel Luis Costa (UFRJ), Roger Chammas (USP) and Thomas Schultheiss (Harvard).

Later, in 2010, during the Celebration of the 40th anniversary of the ICB, we organized the Second Simpósio em Diferenciação Celular do PCM, this time with Mathias Mericskay (Université Paris VI, UMR7079 Physiologie et Physiopathologie), Simon Hughes (MCR Center for Developmental Neurobiology/UK), Daniel Hartline (University of Hawaii/USA) and John Murray (University of Pennsylvania/USA).

The present Simposium is organized by prof Manoel Luis Costa, of the ICB, and by the Cell Differentiation Program of the ICB.

More information:
Programa de Pós-Graduação em Ciências Morfológicas - Bloco K
Centro de Ciências da Saúde - bloco F
Cidade Universitária - Ilha do Fundão
Rio de Janeiro, RJ - Zip 21949-900
Secretary: (21) 2562-6480

Presentation abstracts and selected links:

Myogenesis - Manoel Luis Costa
Skeletal muscle determination begins with molecules secreted from the neural tube and notochord, such as wingless (Wnt) and sonic hedgehog (Shh). These molecules in turn induce the expression of muscle regulatory genes such as myoD and myf, which control all the features of the muscle differentiation program, including cell cycle withdrawal, alignment and fusion between myoblasts, and changes in reticulum and mitochondria. These master switches control the expression of muscle-specific cytoskeletal and adhesion proteins, either directly or through the regulation of muscle differentiation genes such as mgn and MRF4. Many of the myogenic processes require specific cytoskeletal, membrane, and adhesion proteins. For instance, the assembly of the contractile apparatus is based on the regulated expression of muscle-specific actin and myosin. The changes in cell shape are caused by the rearrangement of microtubules. Alignment depends on extracellular clues and fusion is a consequence of interactions between membrane proteins.
Review Article: Cytoskeleton and Adhesion in Myogenesis

by: Prof. Manoel Luís Costa

Rio, 10/2/2014

9:00-9:15	Cláudia Mermelstein	Abertura
9:15-10:00	Radovan Borojevic	Cell Differentiation
10:00-10:20	Manoel Luis Costa	Myogenesis
10:20-10:40	João Menezes	Neurogenesis
10:40-11:00	intervalo
11:00-11:20	Marcia Cury	Differentiation in the Imune System
11:20-11:40	Leonardo Andrade	Differentiation in Epithelial Cells Sensorias
11:40-12:00	Maria Isabel Rossi	Mesechimal Stem Cell Differentiation
12:00-12-30	Roger Chammas	Comparative analysis and discussion

data	2af - 12/3	3af – 13/3	4af - 14/3	5af - 15/3	6af - 16/3
professor	Claudia Mermelstein	Morgana Lima	Leonardo Andrade	João Menezes	Márcia Cury
model	muscle	limphocytes and macrophages	keratinocytes and inner ear tissue explants	neural tissue	bone marrow